Correlation Between Platelet Level and Serological Results in Dengue Patients

Abstract

Summary. Some regions in Indonesia, including Medan, North Sumatra, are endemic areas of dengue fever. According to a report from the Dinkes Provsu, there were 15 death caused by dengue in 2014. After fever, most patients usually experience thrombocytopenia which increases the risk of bleeding and complications. Objectives. This study aims to look at the correlation between platelet levels and serological results in dengue patients at USU Hospital. Material and methods. After gathering ethical clearance, blood samples were taken to the subjects. The selected subjects were tested for platelet using the Sysmex XT-2000i with impedance method. NS1 examination was performed using the Dengue NS1 Ag Kit Bio Line, while for IgM and IgG were performed with the Dengue IgG / IgM test Smart Diagnostic. Data analysis with independent t test. Result. This study gathered that there was a correlation between platelet levels and IgM serological results (p = 0.034) and IgG (p = 0.0049) in dengue patients at USU Hospital, but correlation was found between platelet levels and NS1 (p = 1.000).