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dc.contributor.authorWinata, Hanafis Sastra
dc.contributor.authorRosidah, Rosidah
dc.contributor.authorSitorus, Panal
dc.date.accessioned2018-04-16T13:11:14Z
dc.date.available2018-04-16T13:11:14Z
dc.date.issued2018
dc.identifier.otherElisa Ekaningsih
dc.identifier.urihttp://repository.usu.ac.id/handle/123456789/69281
dc.descriptionPanal Sitorusid
dc.description.abstractObjective: The objective of this study was to evaluate the anti-inflammatory activity in acute and subacute models of inflammation from ethanolic fruit extract of Asam kandis (Garcinia xanthochymus Hook. f. ex T. Anderson) in animal (rats) models. Methods: Pleliminary phytochemical screening was carried out by using standard procedures.. Assessment of acute and subacute models of inflammation was using carrageenan-induced paw edema method and cotton pellet granuloma method using three dosage treatments; 200 mg/kg BW, 400 mg/kg BW, and 800 mg/kg BW along with a negative control group (0.5% Na CMC) and positive control (Na diclofenac 2.25 mg/kg BW). The inhibition period was observed at 30, 60, 90, 120, 150, and 180 min time intervals. Result: The phytochemical screening showed that the ethanolic fruit extract from Asam kandis contain contains flavonoids, glycosides, steroids, and triterpenoids. The anti-inflammatory result showed that the strongest inhibition produced by ethanolic fruit extract of Asam kandis occurred on the dosage of 800 mg/kg BW compared to the other doses (200 and 400 mg/kg BW) throughout the observation period. Conclusion: This finding indicated that ethanolic fruit extract of Asam kandis (G. xanthochymus Hook. f. ex T. Anderson) might become an interesting candidate for treatment of inflammation.id
dc.language.isoenid
dc.subjectAsam Kandisid
dc.subjectAnti-inflammatoryid
dc.subjectCarrageenanid
dc.subjectPaw Edemaid
dc.subjectCotton Pelletid
dc.titleAssessment Of Anti-Inflammatory Activity Of Ethanolic Extract Of Asam Kandis (Garcinia Xanthochymus Hook. F. EX T. Anderson) Fruitid
dc.typeLecture Papersid


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