Vitamin D Deficiency Occur in Healthy Tropical Country Women, Not Depending on Adipocyte Status
Sari, Dina Keumala
Rasyid, Harun Al
Lipoeto, Nur Indrawaty
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Background: Low circulating of 25-hydroxyvitamin D [25(OH)D] serum may increase risk of morbidity and mortality, especially in obese women and vitamin D deficiency are considered to be new markers for obesity and diabetes mellitus. Objective: We investigated whether vitamin D deficiency occur in normoweight and overweight-obese women who lived in abundant sunlight exposures area such as Indonesia. Design: This was a cross-sectional study, including healthy normoweight women (NG/normoweight group, n=41) and overweight-obese women with no other disease subjects (OG/overweight-obese group, n=41), parameters observed were ethnicity, age, sunlight exposure, way of dressed, sunscreen application, whitening application, and nutrient intake. Other parameters such systolic and diastolic pressure, Body Mass Index (BMI), waist circumference, fat distribution, 25-hydroxyvitamin D, and calcium serum were also included. Results: There were no significant different between the two groups in ethnicity, sunlight exposure, sunscreen and whitening application, and nutrient intake, but there were significant different in systolic (p=0.001) and diastolic pressure (p=0.019), BMI (p=0.001), waist circumference (p=0.001), and fat distribution (p=0.001) between two group. Interestingly, there was found lower 25-hydroxyvitamin D concentration, indicated that vitamin D deficiency happened in healthy tropical country women, but there was no significant different in 25-hydroxyvitamin D (p=0.140) and calcium serum (p=0.464) between the two groups. Conclusions: The results indicated that vitamin D deficiency can be found in tropical country and there was no significant different between normoweight and overweight-obese healthy women. This study reported that normoweight and overweight-obese healthy women have hypovitaminosis with different possibility caused, in normoweight probably because of lack of vitamin D intake and less UV B exposure, but in overweight-obese probably because of the trap of vitamin D in adipocyte and less UV B exposure.