|dc.description.abstract||Objective : To find out the correlation between the level of serum EG-VEGF with the size ant amount of follicles in patients who would be givenan In Vitro Fertilization (IVF) actioninThe Halim’s Clinic of Fertility.
LocationThe research was carried out in the Halim’s Fertility Center, Endocrinology subdivision Department of Obstetricsand Gynecology, H. Adam Malik Central General Hospital.
Design: “cross sectional” by the method of observational analytic approach.
Method : collecting samples through by consecutive samplingwith the establishment of inclusiion dan exclusion critetria until the number of minimum samples were fulfiled. The data were showed in the form of average level (Mean) and standard deviation (SD). The analytic statistics used were Correlation Test in a Pearson’s linear regression model (numeric variable). The selection of test depends on the variable types correlated.The comparative analysis of numeric variables (Diameter measurement of follicles, numberof folliclesand serum level of EG-VEGF) unpaired using t-independent test.
Results : The characteristics of research samples obtained is that 29 patients who were samples of this research had an average age of 34 yearsold with thestandarddeviationof 5,07. All patients had anaverage body mass index of 24,08 kg/m2, with measurement deviation of 3,72. The average for each level of EG-VEGF, which was 14,19 dan 3593,58 with standard deviation 9,67 and 878,55.Had a follicle diameter 10-21 mm, overall mean of respondents had 10,72 number of follicles with standard deviation of 0,48. There was no association between the diameter of follicles with the serum and follicles level VEGF. p > 0,05 which means there was not enough evidence to state that both variables have a sifnificant correlation. From the t-independent test, p-value was 0,000 (<0,05) showing that between the serum level and the follicle level have a mean EG-VEGF which is significantly different in confidence interval of 95%.
Conclusion: The larger and thelotsize of diameterandnumber of follicleshad no effect onserumandfollicular fluidlevelsofEG-VEGF, this is because theexpressionofEG-VEGFis notonlylocalizedingranulosaandthecaovarian||en_US