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Please use this identifier to cite or link to this item:
http://repository.usu.ac.id/handle/123456789/29638
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| Title: | Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ruku-Ruku (Ocimum sanctum L.) dan Formulasi Sediaan Obat Kumur-Kumur |
| Authors: | Akarina, Widya |
| Advisors: | Sinaga, Kasmirul Ramlan
Sitompul, Erly |
| Issue Date: | 19-Oct-2011 |
| Abstract: | Ruku-ruku leave (Ocimum sanctum L.) is part of plant with various use such as for the stomachage, antihistamine, injury wash, and toothache. In the last time, the people use the ruku-ruku leave for treatment of toothache. Therefore it is important to study the useful of the ruku-ruku leave.
This research conduct a test of antibacterial activity on ethanol extract of ruku-ruku leave and the formulation of mouthwash that contain ethanol extract from ruku-ruku leave to the bacteria of Staphylococcus aureus, Streptococcus mutans and Streptococcus sp. (isolated bacteria from specimen) in vitro using agar diffusion method by metal cylinder disk. The sample of ruku-ruku leave took purposively at Jalan Selamat No. 80, Subdistrict of Medan Amplas, Medan.
Antibacterial activity provide of ethanol extract of ruku-ruku leave indicates that the minimum blocked concentration to the Staphylococcus aureus, Streptococcus mutans and Streptococcus sp. bacteria (isolated bacteria from specimen) is 40 mg/ml. The ethanol extract of ruku-ruku leave has an effective blocked to the concentration of 90 mm/ml to the bacteria of staphylococcus aureus in 14 mm in diameter on the concentration 80 mg/ml to the bacteria Streptococcus mutans on 14.3 mm in diameter on concentration 90 mg/ml to the bacteria Streptococcus sp. (isolated bacteria from specimen) with diameter 14.7 mm. The testing on ethanol extract ruku-ruku leave of mouthwash on F1, FII, and FIII provide the block zone diameter that satisfy the three of bacteria with the diameter more than 14 mm to the bacteria Strepotococcus mutans, Staphylococcus aureus, and Streptococcus sp. (Isolated bacteria from specimen). |
| Abstract (other language): | Daun tumbuhan ruku-ruku (Ocimum sanctum L.) merupakan salah satu bagian tanaman yang perlu dikembangkan manfaatnya, misalnya untuk mengobati sakit perut, batuk, pencuci luka dan sakit gigi. Selama ini masyarakat menggunakan daun ruku-ruku sebagai obat sakit gigi, oleh karena itu perlu dilakukan penelitian pemanfaatan daun ruku-ruku.
Pada penelitian ini dilakukan uji aktivitas antibakteri ekstrak etanol daun ruku-ruku dan sediaan obat kumur yang mengandung ekstrak etanol daun ruku-ruku terhadap bakteri Staphylococcus aureus, Streptococcus mutans dan Streptococcus sp. (bakteri isolasi dari specimen) yang dilakukan secara invitro memakai metode difusi agar dengan cakram silinder logam. Sampel daun ruku-ruku diambil secara purposif dari jalan Selamat No. 80, Kecamatan Medan Amplas, Medan.
Hasil aktivitas antibakteri dari ekstrak etanol daun ruku-ruku menunjukkan bahwa konsentrasi hambat minimum terhadap bakteri Staphylococcus aureus, Streptococcus mutans dan Streptococcus sp (bakteri isolasi dari specimen) yaitu sebesar 40 mg/ml. Ekstrak etanol daun ruku-ruku memberikan batas daerah hambat yang efektif pada konsentrasi 90 mg/ml terhadap bakteri Staphylococcus aureus dengan diameter 14 mm pada konsentrasi 80 mg/ml terhadap bakteri Streptococcus mutans dengan diameter 14,3 mm pada konsentrasi 90 mg/ml terhadap bakteri Streptococcus sp (bakteri isolasi dari specimen) dengan diameter 14,7 mm. Pengujian sediaan obat kumur-kumur ekstrak etanol daun ruku-ruku pada FI, FII dan FIII memberikan hasil diameter zona hambatan yang memuaskan terhadap ketiga bakteri yaitu lebih besar dari 14 mm terhadap bakteri Streptococcus mutans, Staphylococcus aureus, dan Streptococcus sp. (bakteri isolasi dari specimen). |
| Keywords: | Extract Ruku-Ruku Leave
Antibacterial
Staphylococcus
Streptococcus
Mouthwash |
| URI: | http://repository.usu.ac.id/handle/123456789/29638 |
| Appears in Collections: | SP - Pharmacology
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