Galaktorrea pada Miksedem
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Galactorrhea, or inappropriate lactation, is a relatively common problem that occurs in approximately 20 to 25 percent of women. In response to the hypothyroid state, a compensatory increase in the discharge of central hypothalamic thyrotropin releasing hormone results in increased stimulation of prolactin secretion. Furthermore, prolactin elimination from the systemic circulation is reduced, which contributes to increased prolactin concentrations, diffuse pituitary enlargement, which will reverse with appropriate thyroid hormone replacement therapy.