Femur Metastase Papillary Carcinoma of The Thyroid
Alferraly, T. Ibnu
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We report a case of a 47-year-old woman who presented with a diffuse mass on her left thigh. FNAB was done and resulted in a bloody aspirate, approximately ± 5 cc. The preparation is stained with MGG and appeared in microscopic of micropapillary cluster with some rosetting structure. The cytologic featured nuclear enlargement and anisokaryosis that was relevant with metastases of papillary carcinoma of the thyroid. A papillary carcinoma of the thyroid with bone metastases is a rare case because distant metastases are less frequent in papillary carcinoma of the thyroid than with other thyroid carcinomas (only 5% to 7%), especially in femur. There are multiple criteria must be observed before making a confident cytological diagnosis of papillary carcinoma of the thyroid. Analysis of various criteria suggested that a combination of intranuclear cytoplasmic inclusions, papillary structures and dense cytoplasm were the three most important variables. With sensitivity and predictive value of cytological diagnosis ranged from 60% to 90%. But we should not forget, always confirm with the histopathology for the final diagnosis because cytology is not one definitive diagnosis.