Parascreen as an Alternative Diagnostic Tool for Falciparum Malaria
Lubis, Chairuddin P.
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Background Malaria is a parasitic disease with high morbidity and mortality. Rapid immunochromatographic are emerging to detect specific antigens of human plasmodia. Objective To determine the sensitivity and specificity of Para screen for the detection of Plasmodium falciparum in children. Methods A diagnostic test study was performed in Mandailing Natal District, Penyabungan, North Sumatera. Subjects were public health center and hospital patients with symptoms of fever, pallor, headache, and diarrhea. Blood specimens were obtained for Parascreen testing. Microscopy of Giemsa-stained blood samples served as the gold standard. Results One hundred and four subjects were studied. The sensitivity and specificity of Para screen were 76% and 100%, respectively. Positive and negative predictive values of the test were 100% and 49%, respectively. Likelihood ratio was infinite for a positive test and 0.23% for a negative test. Conclusion Parascreen is a useful and highly specific diagnostic tool for P. falciparum malaria